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KMID : 0364020180510010022
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Korean Journal of Thoracic and Cardiovascular Surgery
2018 Volume.51 No. 1 p.22 ~ p.28
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Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center
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Jeong Yong-Ho
Choi Se-Hoon
Park Seung-Il
Kim Dong-Kwan
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Abstract
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Background: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea.
Methods: We retrospectively evaluated the outcomes of patients who received a lung transplant at Asan Medical Center between January 2008 and December 2016. Thirteen of 54 patients experienced multiorgan transplantation; the remaining 41 who received only lung grafts were included.
Results: The mean age of the lung transplant recipients was 44.6 years; 27 were men and 14 were women. The most frequent reasons were idiopathic interstitial pneumonia (21 of 41 patients, 51.2%), interstitial lung disease (9 of 41, 22.0%), and bronchiolitis obliterans after bone marrow transplantation (7 of 41, 17.1%). The median waiting time was 47 days, and many patients received preoperative intensive care (27 of 41, 65.9%), ventilator support (26 of 41, 63.4%), or extracorporeal life support (19 of 41, 46.3%). All 41 patients received bilateral lung grafts. Ten deaths occurred (24.3%), including 5 cases of early mortality (12.2%) and 5 cases of late mortality (12.2%). The 1-, 3-, and 5-year survival rates were 78.9%, 74.2%, and 69.3%, respectively.
Conclusion: Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable.
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KEYWORD
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Lung transplantation, Extracorporeal membrane oxygenation (ECMO), Survival
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